The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2017

Filed:

Dec. 28, 2012
Applicant:

Tao Health Life Pharma Co., Ltd.;

Inventor:

Minako Hoshi, Kyoto, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/08 (2006.01); A61K 38/13 (2006.01); A61K 38/00 (2006.01); C07K 5/117 (2006.01); A61K 38/17 (2006.01); A61K 31/554 (2006.01); G01N 33/68 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 5/107 (2006.01); C07K 5/11 (2006.01);
U.S. Cl.
CPC ...
C07K 5/1024 (2013.01); A61K 31/554 (2013.01); A61K 38/13 (2013.01); A61K 38/1767 (2013.01); A61K 51/08 (2013.01); C07K 5/1016 (2013.01); C07K 5/1019 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); G01N 33/6896 (2013.01); A61K 38/00 (2013.01); G01N 2500/02 (2013.01); G01N 2800/2821 (2013.01);
Abstract

In one or a plurality of embodiments, there is provided a target molecule of amylospheroid, which is expressed in mature neurons and to which the amylospheroid binds to induce death of cells. Further, in one or a plurality of embodiments, there is provided a method and a substance for inhibiting death of mature neurons induced by the amylospheroid. In one aspect, the present disclosure relates to a use of Na/K-ATPase α3 as a binding target molecule of amylospheroid. In another aspect, the present disclosure relates to a method for suppressing death of mature neurons induced by the amylospheroid, including inhibiting protein-protein interaction between the amylospheroid and the Na/K-ATPase α3, and the like.


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