The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2017

Filed:

Nov. 26, 2014
Applicants:

Crystal Pharmatech Inc., North Brunswick, NJ (US);

Suzhou Pengxu Pharmatech Co., Ltd., Suzhou, CN;

Inventors:

Minhua Chen, Scotch Plains, NJ (US);

Yanfeng Zhang, Suzhou, CN;

Chaohui Yang, Suzhou, CN;

Xiaoyu Zhang, Suzhou, CN;

Peng Wang, Forest Hills, NY (US);

Pixu Li, Suzhou, CN;

Fei Lu, Suzhou, CN;

Heng Ge, Suzhou, CN;

Assignees:

Crystal Pharmatech Inc., North Brunswick, NJ (US);

Suzhou Pengxu Pharmatech Co., Ltd., Suzhou, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); C07D 487/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); C07B 2200/13 (2013.01);
Abstract

Crystalline Form I of ibrutinib, processes for its preparation, pharmaceutical compositions comprising the new Form, and use of Form I of ibrutinib for treating or delaying diseases or disorders related to activity of Bruton's tyrosine kinase (BTK) proteins are disclosed. The novel Form was characterized by X-ray powder diffraction, differential scanning calorimetry, and other techniques. It can be readily prepared and is suitable for use in the preparation of solid dosage forms.


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