The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 2017
Filed:
Oct. 13, 2016
Applicant:
National Institute of Biological Sciences, Beijing, Beijing, CN;
Inventors:
Assignee:
National Institute of Biological Sciences, Beijing, Beijing, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/53 (2006.01); C07D 251/72 (2006.01); A61K 45/06 (2006.01); C07D 251/10 (2006.01);
U.S. Cl.
CPC ...
C07D 251/72 (2013.01); A61K 31/53 (2013.01); A61K 45/06 (2013.01); C07D 251/10 (2013.01);
Abstract
The invention provides novel compounds and compositions comprising a 5-HTantagonist of formula I: and related methods for treating a person having a disorder characterized by undesirable 5-HTreceptor signaling, such as migraine, irritable bowel syndrome (IBS), pulmonary arterial hypertension (PAH), fibrosis, hepatocellular cancer, a small intestinal neuroendocrine tumor, cardiovascular disorders, and gastrointestinal (GI) tract disorders.