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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9751844 B1

PDFFull Text
Date of Patent:
Sep. 05, 2017

Filed:

Dec. 13, 2011

Precursor compound connected to solid support for manufacturing 18f radiopharmaceutical, method for manufacturing same, and application thereof

Applicants:

Dae-yoon Chi, Seoul, KR;

Byoung-se Lee, Seoul, KR;

Jae-hak Lee, Incheon, KR;

So-young Chu, Seoul, KR;

Woon-jung Jung, Seoul, KR;

Hye-rim Kwon, Incheon, KR;

Inventors:

Dae-Yoon Chi, Seoul, KR;

Byoung-Se Lee, Seoul, KR;

Jae-Hak Lee, Incheon, KR;

So-Young Chu, Seoul, KR;

Woon-Jung Jung, Seoul, KR;

Hye-Rim Kwon, Incheon, KR;

Assignee:

FUTURECHEM CO., LTD., Seoul, KR;

Attorney:

Renner, Otto, Boisselle & Sklar, LLP

Primary Examiner:

Paul Dickinson

Int. Cl.
CPC ...
A61K 9/00 (2006.01); C07D 249/04 (2006.01); A61K 51/04 (2006.01); C07B 59/00 (2006.01); C07C 229/60 (2006.01); C07D 403/12 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01); C07H 19/06 (2006.01); C08F 212/08 (2006.01); C08F 212/14 (2006.01); C08F 8/02 (2006.01); C08F 8/30 (2006.01); C08F 8/34 (2006.01); C08F 8/44 (2006.01); C08F 12/26 (2006.01); C08F 12/30 (2006.01); C08F 212/32 (2006.01);
U.S. Cl.
CPC ...
C07D 249/04 (2013.01); A61K 51/04 (2013.01); A61K 51/0406 (2013.01); A61K 51/047 (2013.01); A61K 51/0453 (2013.01); A61K 51/0455 (2013.01); A61K 51/0465 (2013.01); A61K 51/0491 (2013.01); C07B 59/00 (2013.01); C07C 229/60 (2013.01); C07D 403/12 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01); C07H 19/06 (2013.01); C08F 8/02 (2013.01); C08F 8/30 (2013.01); C08F 8/34 (2013.01); C08F 8/44 (2013.01); C08F 212/08 (2013.01); C08F 212/14 (2013.01); C08F 12/26 (2013.01); C08F 12/30 (2013.01); C08F 212/32 (2013.01);
Abstract

The present invention relates to a solid precursor in the form of an organic salt, the solid precursor having a solid support, a method for manufacturing same, and an application thereof. The solid precursor of the present invention enables omission of the [F]fluoride refining process using additional cartridge, and the use of excessive phase-transfer catalyst, and can easily remove remaining substance after reaction through the solid support inside the precursor. The solid precursor of the present invention is very appropriate for an automated synthesis device as an all-in-one system that can carry out overall process of [F]fluorosis reaction, when used by charging in a cartridge.

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