The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2017

Filed:

Dec. 21, 2004
Applicants:

Michel Schneider, Troinex, CH;

Philippe Bussat, Feigeres, FR;

Feng Yan, Grand Lancy, CH;

Anne Senente, Carouge, CH;

Inventors:

Michel Schneider, Troinex, CH;

Philippe Bussat, Feigeres, FR;

Feng Yan, Grand Lancy, CH;

Anne Senente, Carouge, CH;

Assignee:

Bracco Suisse S.A., Manno, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 41/00 (2006.01); A61K 49/22 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48869 (2013.01); A61K 41/0028 (2013.01); A61K 49/225 (2013.01);
Abstract

Assembly comprising a gas-filled microvesicle and a structural entity which is capable to associate through an electrostatic interaction to the outer surface of said microvesicle (microvesicle associated component—MAC), thereby modifying the physico-chemical properties thereof. Said MAC may optionally comprise a targeting ligand, a bioactive agent, a diagnostic agent or any combination thereof. The assembly of the invention can be formed from gasfilled microbubbles or microballoons and a MAC having a diameter of less than 100 pm, in particular a micelle and is used as an active component in diagnostically and/or therapeutically active formulations, in particular for enhancing the imaging in the field of ultrasound contrast imaging, including targeted ultrasound imaging, ultrasound-mediated drug delivery and other imaging techniques such as molecular resonance imaging (MRI) or nuclear imaging.


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