The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2017

Filed:

Sep. 16, 2013
Applicant:

The United States of America, As Represented BY the Secretary, Dept. of Health and Human Services, Washington, DC (US);

Inventors:

Madushini Nirosha Dharmasena, Germantown, MD (US);

Dennis J. Kopecko, Silver Spring, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/112 (2006.01); C07H 21/02 (2006.01); A61K 39/00 (2006.01); C07K 14/25 (2006.01); C07K 14/255 (2006.01); C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0283 (2013.01); A61K 39/0275 (2013.01); C07K 14/25 (2013.01); C07K 14/255 (2013.01); C12N 1/20 (2013.01); A61K 2039/522 (2013.01); A61K 2039/523 (2013.01); A61K 2039/542 (2013.01); A61K 2039/70 (2013.01); C07K 2319/40 (2013.01);
Abstract

A recombineeredTy21a, compositions and vaccines comprising such a Ty21a, and a method for recombineering comprising inserting a large antigenic region into a bacterial chromosome for the purpose of making multivalent vaccines to protect against one or more disease agents are described herein.


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