The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2017

Filed:

May. 21, 2015
Applicants:

Robert M. Kottmann, Rochester, NY (US);

Patricia J. Sime, Pittsford, NY (US);

Richard P. Phipps, Pittsford, NY (US);

Inventors:

Robert M. Kottmann, Rochester, NY (US);

Patricia J. Sime, Pittsford, NY (US);

Richard P. Phipps, Pittsford, NY (US);

Assignee:

University of Rochester, Rochester, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 35/00 (2006.01); A61K 31/11 (2006.01); A61K 31/713 (2006.01); A61K 31/404 (2006.01); A61K 45/06 (2006.01); A61K 31/12 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 31/12 (2013.01); A61K 31/404 (2013.01); A61K 45/06 (2013.01); C12N 15/1137 (2013.01); C12Y 101/01027 (2013.01); C12Y 101/01028 (2013.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01);
Abstract

One aspect of the disclosure relates to methods of treating a fibrotic condition in an individual. The methods include administering to an individual having a fibrotic condition an effective amount of a lactic dehydrogenase (LDH) inhibitor, wherein the fibrotic condition involves an internal organ or tissue, or ocular tissue, and said administering is effective to treat the fibrotic condition. Methods of administration and pharmaceutical compositions and systems for practicing such methods are also disclosed.


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