The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2017

Filed:

Mar. 04, 2016
Applicants:

Richard P. Phipps, Pittsford, NY (US);

Naxin Guo, Rochester, NY (US);

Steven Feldon, Rochester, NY (US);

Inventors:

Richard P. Phipps, Pittsford, NY (US);

Naxin Guo, Rochester, NY (US);

Steven Feldon, Rochester, NY (US);

Assignee:

University of Rochester, Rochester, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 31/506 (2006.01); A61K 31/519 (2006.01); A61K 31/557 (2006.01); A61K 31/166 (2006.01); A61K 31/403 (2006.01); A61K 31/5575 (2006.01); A61K 31/7105 (2006.01); C12N 15/113 (2010.01); A61K 31/201 (2006.01); A61K 31/713 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/557 (2013.01); A61K 31/166 (2013.01); A61K 31/201 (2013.01); A61K 31/403 (2013.01); A61K 31/4439 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01); A61K 31/5575 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); C12N 15/1137 (2013.01); A61K 9/0048 (2013.01); C12N 2310/14 (2013.01); C12N 2320/31 (2013.01); Y10S 514/912 (2013.01);
Abstract

The present invention relates to a methods and compositions for the treatment of and management of symptoms for thyroid eye disease. The methods include administering to a patient having thyroid eye disease an agent that interferes with hyaluronan synthesis in an amount that is effective to inhibit hyaluronan synthesis in a retro-ocular space. The pharmaceutical compositions that includes a carrier suitable for ophthalmic delivery and an agent that interferes with hyaluronan synthesis. Combination therapies are also disclosed.


Find Patent Forward Citations

Loading…