The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 2017
Filed:
May. 14, 2009
Leigh Zawel, Weston, MA (US);
Christopher S. Straub, Stow, MA (US);
Brant G. Firestone, Westwood, MA (US);
Glenn Dranoff, Lexington, MA (US);
Michael Dougan, Brookline, MA (US);
Leigh Zawel, Weston, MA (US);
Christopher S. Straub, Stow, MA (US);
Brant G. Firestone, Westwood, MA (US);
Glenn Dranoff, Lexington, MA (US);
Michael Dougan, Brookline, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Novartis AG, Basel, CH;
Abstract
The present invention is directed to immune adjuvants containing IAP inhibitors, including Smac mimetics. The invention further provides pharmaceutical compositions and vaccines containing an IAP inhibitor and an antigen. Methods of enhancing an immune response by administration of an IAP inhibitor, methods of treating or preventing cancer, methods of treating or preventing infections, methods of treating autoimmune disorders, and methods of potentiating cytokine or antibody production are also provided.