The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2017

Filed:

Oct. 31, 2014
Applicant:

Ohio University, Athens, OH (US);

Inventors:

Kelly D. McCall, Athens, OH (US);

Frank L. Schwartz, Vienna, WV (US);

Douglas J. Goetz, Athens, OH (US);

Ramiro Malgor, Athens, OH (US);

Assignee:

Ohio University, Athens, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); A61K 31/4184 (2006.01); A61K 31/4164 (2006.01); C07D 233/84 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4184 (2013.01); A61K 31/4164 (2013.01); A61K 45/06 (2013.01); C07D 233/84 (2013.01);
Abstract

Methods for preventing, treating, and/or reducing the risk of developing non-alcoholic fatty liver disease in a subject in need thereof and pharmaceutical compositions for the prevention or treatment of non-alcoholic fatty liver disease. The methods include administering a therapeutically effective amount of phenylmethimazole, methimazole derivatives, and/or tautomeric cyclic thiones to the subject. The pharmaceutical composition includes phenylmethimazole, methimazole derivatives, and/or tautomeric cyclic thiones formulated for administration to a subject for the prevention or treatment of non-alcoholic fatty liver disease.


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