The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2017
Filed:
Nov. 04, 2015
Applicant:
Vanderbilt University, Nashville, TN (US);
Inventors:
Christopher Chad Quarles, Nashville, TN (US);
John C. Gore, Nashville, TN (US);
Natenael B. Semmineh, Nashville, TN (US);
Assignee:
VANDERBILT UNIVERSITY, Nashville, TN (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2006.01); G01R 33/50 (2006.01); G01R 33/56 (2006.01);
U.S. Cl.
CPC ...
G06K 9/00127 (2013.01); G01R 33/50 (2013.01); G01R 33/5601 (2013.01);
Abstract
In the various embodiments, cell size imaging is performed using a method that relies upon the acquisition of gradient echo and spin echo data during contrast agent (CA) passage through tissue and estimation of 'perturber' size using the ratio of ΔR* and ΔR. When measured at CA equilibrium, the magnetic field perturbations, and associated MRI signal changes, are determined by the cellular features and not the vasculature. Thus, in cell size imaging the cells act as the perturbers.