The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2017

Filed:

Jun. 22, 2015
Applicant:

Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US);

Inventors:

Tie Quan Wei, Wilmington, DE (US);

Jie Li, Middletown, DE (US);

Manoj Sharma, Hockessin, DE (US);

Zhu Teng, Garnet Valley, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/82 (2006.01); G01N 33/532 (2006.01); C07K 16/44 (2006.01); A61K 39/385 (2006.01); G01N 21/76 (2006.01); C07C 401/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/82 (2013.01); C07K 16/44 (2013.01); A61K 39/385 (2013.01); C07C 401/00 (2013.01); G01N 21/76 (2013.01); G01N 33/532 (2013.01);
Abstract

Methods include determining an amount of vitamin D analyte in a sample suspected of containing the vitamin D analyte. A combination is provided in an assay medium that includes the sample, a vitamin D epimer antibody that is specific for epimers of the vitamin D analyte wherein the vitamin D epimer antibody does not bind to any detectable degree to the vitamin D analyte, and a vitamin D antibody that is specific for the vitamin D analyte, and. The assay medium is incubated under conditions for binding of the vitamin D epimer antibody to the epimers of the vitamin D analyte and for binding of the vitamin D antibody to the vitamin D analyte to form a vitamin D antibody-bound complex. The amount of vitamin D antibody-bound complex is determined and related to the amount of vitamin D analyte in the sample.


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