The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2017

Filed:

Feb. 20, 2012
Applicants:

Christoph Wittmann, Wolfenbuettel, DE;

Stefanie Kind, Braunschweig, DE;

Inventors:

Christoph Wittmann, Wolfenbuettel, DE;

Stefanie Kind, Braunschweig, DE;

Assignee:

BASF SE, Ludwigshafen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 15/00 (2006.01); C12P 13/02 (2006.01); C07H 21/04 (2006.01); A61K 38/00 (2006.01); C12N 15/77 (2006.01); C12N 9/88 (2006.01); C07K 14/34 (2006.01); C12P 13/00 (2006.01);
U.S. Cl.
CPC ...
C12P 13/02 (2013.01); C07K 14/34 (2013.01); C12N 9/88 (2013.01); C12N 15/77 (2013.01); C12P 13/001 (2013.01);
Abstract

Recombinant microorganisms comprising DNA molecules in a deregulated form which improve the production of cadaverine or N-acetylcadaverine, as well as recombinant DNA molecules and polypeptides used to produce the microorganisms are provided. Said microorganisms comprise an intracellular lysine decarboxylase activity and a deregulated cadaverine export activity, or comprise a decreased cadaverine export activity and an enhanced N-acetylcadaverine forming activity. Processes for the production of cadaverine N-acetylcadaverine using the recombinant microorganisms are also provided.


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