The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2017

Filed:

Apr. 18, 2013
Applicants:

Somar Corp., Tokyo, JP;

Toshihiro Akaike, Tokyo, JP;

Inventors:

Amranul Haque, Yokohama, JP;

Masato Nagaoka, Brookfield, WI (US);

Toshihiro Akaike, Tokyo, JP;

Assignees:

SOMAR CORP., Tokyo, JP;

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12N 5/0797 (2010.01); C12N 5/079 (2010.01); C12N 5/0735 (2010.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0623 (2013.01); C12N 5/0606 (2013.01); C12N 5/0618 (2013.01); C12N 5/0696 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01); C12N 2533/30 (2013.01); C12N 2533/50 (2013.01);
Abstract

[Problem] To provide a cell culture substrate, and a cell culturing method using the substrate and a method for inducing differentiation of pluripotent stem cells using the substrate, which allow culturing of pluripotent stem cells and allow differentiation of pluripotent stem cells into a specified cell species, particularly neural and neural progenitor cells, at a high purity. [Means for Solution] A cell culture substrate, characterized in that, onto the surface, one or more selected from the group consisting of N-cadherin, a fusion protein comprising an entire or partial region of N-cadherin, and a fusion protein comprising an entire or partial region of a protein homologous to N-cadherin are immobilized or coated.


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