The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2017
Filed:
Mar. 17, 2017
Beijing Mabworks Biotech Co. Ltd, Beijing, CN;
Feng Li, Beijing, CN;
Boyan Zhang, Foster City, CA (US);
Pei Ye, Lowarenceville, GA (US);
Jian Zhao, Beijing, CN;
Sijia Huang, Beijing, CN;
Chunyang Jin, Beijing, CN;
Beijing Mabworks Biotech Co. Ltd., Beijing, CN;
Abstract
The present invention relates to humanized bispecific anti-HER2 antibodies that comprise one antigen binding site containing variable regions of heavy and light chain of trastuzumab, and another antigen binding site containing variable regions of heavy and light chain of pertuzumab. The bispecific anti-HER2 antibodies is effective for treating cancer, such as breast cancer, gastric cancer, or ovarian cancer. Preferred bispecific anti-HER antibodies of the present invention are afucosylated antibodies.