The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2017

Filed:

Nov. 16, 2015
Applicant:

Nanjing Medical University, Nanjing, CN;

Inventors:

Jianwei Zhou, Nanjing, CN;

Jin Xu, Nanjing, CN;

Xuan Li, Nanjing, CN;

Aiping Li, Nanjing, CN;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); C07K 7/08 (2006.01); A61K 38/00 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 14/4703 (2013.01); A61K 38/00 (2013.01);
Abstract

An anti-tumor polypeptide, having an amino acid sequence represented by FPGSDRF (SEQ ID NO: 15), X-FPGSDRF (SEQ ID NO: 16), FPGSDRF-Z (SEQ ID NO: 17), or X-FPGSDRF-Z (SEQ ID NO: 18) is disclosed. The various capital letters denote amino acids: F: phenylalanine; P: proline; G: glycine; D: aspartic acid; R: arginine; S is a phosphorylated serine residue, X and Z are an amino acid residue or an amino acid sequence, respectively, X is one selected from the group consisting of F, (R)(SEQ ID NO: 19), (R)-F (SEQ ID NO: 20), 6-aminocaproic acid, 6-aminocaproic acid-F, 6-aminocaproic acid-(R)(SEQ ID NO: 21), and 6-aminocaproic acid-(R)-F (SEQ ID NO: 22), Z is one selected from the group consisting of A, (G)-RGD (SEQ ID NO: 23), and A-(G)-RGD (SEQ ID NO: 24); and n is an integer greater than or equal to 0.


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