The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2017

Filed:

Sep. 17, 2014
Applicant:

Shanghai Yingli Pharmaceutical Co., Ltd, Shanghai, CN;

Inventor:

Zusheng Xu, Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); C07D 493/04 (2006.01); C07D 491/04 (2006.01); C07D 491/048 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); C07D 491/048 (2013.01); C07D 493/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Disclosed are a fused pyrimidine compound, an intermediate, a preparation method therefor, and a composition and an application thereof. The present invention provides a fused pyrimidine compound shown in formula I, pharmaceutically acceptable salt, hydrate, solvate, and an optical isomer or prodrug of the compound. The present invention further provides applications of the fused pyrimidine compound shown in formula I, the pharmaceutically acceptable salt, the hydrate, solvate, and the optical isomer or the prodrug of the compound in the preparing drugs for curing and/or preventing a kinase-related disease. The fused pyrimidine compound I of the present invention is an efficient PI3 kinase depressor, and can be used to prepare drugs for preventing and/or curing cell-proliferation diseases such as cancer, infection, inflammation, and an autoimmune disease.


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