The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2017
Filed:
Jan. 17, 2014
Applicant:
Shanghai Chemexplorer Co., Ltd., Shanghai, CN;
Inventors:
Zusheng Xu, Shanghai, CN;
Nong Zhang, Shanghai, CN;
Qingrui Sun, Shanghai, CN;
Tinghan Wang, Shanghai, CN;
Assignee:
GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD., Guangzhou, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); C07D 491/048 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 31/519 (2013.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01);
Abstract
A five-and-six-membered heterocyclic compound as represented by general formula I, pharmaceutically acceptable salt, metabolite, metabolic precursors or drug precursors thereof, preparation method, pharmaceutical composition, and use thereof; the five-and-six-membered heterocyclic compound has activity as a Janus kinase (JAK) inhibitor, and can be used to prepare drugs for treating diseases caused by the abnormal activity of kinase, such as cell proliferation diseases like cancer.