The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2017
Filed:
Apr. 25, 2014
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Jongwon Lim, Lexington, MA (US);
Xianhai Huang, Warren, NJ (US);
Ronald D. Ferguson, Scotch Plains, NJ (US);
Wei Zhou, Scotch Plaines, NJ (US);
Christopher W. Boyce, Flemington, NJ (US);
Phieng Siliphaivanh, Newton, MA (US);
David J. Witter, Norfolk, MA (US);
Milana M. Maletic, Summit, NJ (US);
Joseph A. Kozlowski, Princeton, NJ (US);
Kevin J. Wilson, Boston, MA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
Disclosed are the ERK inhibitors of formula (I) and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (I). This invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of formula (I) and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of formula (I) and an effective amount of at least one other pharmaceutically active ingredient (such as, for example, a chemotherapeutic agent), and a pharmaceutically acceptable carrier. This invention also provides a method of inhibiting ERK (i.e., inhibiting the activity of ERK2) in a patient in need of such treatment comprising administering to said patient an effective amount of at least one compound of formula (I).