The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2017
Filed:
Nov. 07, 2013
Selvita SA, Kraków, PL;
Tomasz Rzymski, Elblag, PL;
Adrian Zarebski, Kraków, PL;
Agnieszka Dreas, Poznan, PL;
Karolina Osowska, Kraków, PL;
Katarzyna Kucwaj, Kraków, PL;
Joanna Fogt, Leszno, PL;
Marek Cholody, Kraków, PL;
Michal Galezowski, Skierniewice, PL;
Wojciech Czardybon, Mikolów, PL;
Raymond Horvath, Montreal, CA;
Katarzyna Wiklik, Kraków, PL;
Mariusz Milik, Kraków, PL;
Krzysztof Brzózka, Kraków, PL;
SELVITA SA, Cracow, PL;
Abstract
Disclosed are substituted tricyclic benzimidazoles compounds as defined herein in formula (I) or pharmaceutically acceptable salts thereof. The compounds of the invention selectively inhibit CDK8 and are therefore useful for treating diseases related to this kinase, especially colorectal and melanoma cancers and other solid and hemathological malignancies, autoimmune diseases and inflammatory diseases. Also disclosed are processes for preparing these compounds.