The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2017

Filed:

Mar. 14, 2014
Applicants:

Bionomics Limited, Thebarton, South Australia, AU;

Ironwood Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Bernard Luke Flynn, Donvale, AU;

Dharam Paul, Flinders Park, AU;

Andrew John Harvey, Goodwood, AU;

Vasu V. Sethuraman, Waltham, MA (US);

Raymond E. Forslund, Natick, MA (US);

Song Xue, Newton, MA (US);

Rob Livingston, Cambridge, MA (US);

Ahmad Hashash, Cambridge, MA (US);

Assignees:

BIONOMICS LIMITED, Thebarton, South Australia, AU;

IRONWOOD PHARMACEUTICALS, INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/4375 (2006.01); C07C 55/10 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07C 55/10 (2013.01);
Abstract

The present invention provides amorphous arid crystalline forms of 1-ethyl-6-(indan-2-ylamino)-3-(morpholine-4-carbonyl)-1,8-naphthyridin-4-one (compound 1), and salts, co-crystals, and pharmaceutical compositions thereof. The invention also provides methods of treating and/or preventing a disease, such as a central nervous system disease (e.g., an anxiety disorder), using the amorphous and crystalline forms, and salts, co-crystals, and pharmaceutical compositions thereof.


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