The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2017
Filed:
Jul. 22, 2016
Snu R&db Foundation, Seoul, KR;
Young-Ger Suh, Seoul, KR;
Hongchan An, Seoul, KR;
Seungbeom Lee, Seoul, KR;
Kyu-Won Kim, Seoul, KR;
Ho-Young Lee, Seoul, KR;
Sang Geon Kim, Seoul, KR;
Jeong Hun Kim, Seoul, KR;
SNU R&DB FOUNDATION, Seoul, KR;
Abstract
A compound inhibiting Hsp90 and a pharmaceutical composition including the same as an active ingredient are described, which compound is represented by formula 2 and suppresses the expression of Hsp90, inhibits the accumulation of HIF-1α, the Hsp90 client protein, and efficiently inhibits the activation of VEGF. The compound displays low cytotoxicity and can be effectively used as an active ingredient of an anti-cancer agent, a diabetic retinopathy treating agent, and an anti-arthritic agent.