The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2017
Filed:
Sep. 10, 2008
Chiang Jia LI, Cambridge, MA (US);
Harry Rogoff, Wrentham, MA (US);
Youzhi LI, Westwood, MA (US);
Jifeng Liu, Winchester, MA (US);
Wei LI, Wayland, MA (US);
Chiang Jia Li, Cambridge, MA (US);
Harry Rogoff, Wrentham, MA (US);
Youzhi Li, Westwood, MA (US);
Jifeng Liu, Winchester, MA (US);
Wei Li, Wayland, MA (US);
Boston Biomedical, Inc., Cambridge, MA (US);
Abstract
The present invention relates to the use of a novel class of cancer stem cell pathway (CSCP) inhibitors; to methods of using such compounds to treat refractory, recurrent, or metastatic cancers; to methods of selective killing cancer cells by using such compounds with specific administration regimen; to methods of targeting cancer stem cells by inhibiting Stat3 pathway; to methods of using novel compounds in the treatment of conditions or disorders in a mammal related to aberrant Stat3 pathway activity; and to processes for preparing such compounds and intermediates thereof, and to the pharmaceutical composition of relevant compounds, and to the specific methods of administration of these compounds.