The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2017

Filed:

Oct. 20, 2014
Applicants:

Shanghai Syncores Technologies, Inc., Shanghai, CN;

Zhejiang Huahai Pharmaceuticals Co., Ltd., Zhejiang, CN;

Inventors:

Hong Gu, Shanghai, CN;

Jian Cao, Shanghai, CN;

Liushan Chen, Shanghai, CN;

Luning Huang, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/08 (2006.01); C07C 51/41 (2006.01); C07C 59/255 (2006.01); C07C 303/32 (2006.01); C07C 309/25 (2006.01);
U.S. Cl.
CPC ...
C07D 209/08 (2013.01); C07C 51/41 (2013.01); C07C 59/255 (2013.01); C07C 303/32 (2013.01); C07C 309/25 (2013.01); C07C 2602/42 (2017.05);
Abstract

Provided is a method for preparing silodosin. Also provided is a method for preparing an organic acid salt of a new intermediate 3-(7-cyano-5-((R)-2-((R)-1-phenylethylamino)propyl)-1-hydrogen-indolyl) propyl alcohol (ester or ether), and a new intermediate 3-(7-cyano-5-((R)-2-(((R)-1-phenethyl)(2-(2-(trifluoroethoxy)phenoxy) ethyl)amino)propyl)1-hydrogen-indolyl)propyl alcohol (ester or ether) and a salt thereof. The method has the following advantages: raw materials are cheap and easy to obtain, the operation is simple, the intermediate and product are easy to purify, the yield is high, and the method is applicable to industrial production.


Find Patent Forward Citations

Loading…