The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2017
Filed:
Feb. 18, 2014
The Regents of the University of California, Oakland, CA (US);
Fondazione Istituto Italiano Di Tecnologia, Genoa, IT;
Universita Degli Studi Di Urbino “carlo Bo”, Urbino, IT;
Universita Degli Studi Di Parma, Parma, IT;
Daniele Piomelli, Irvine, CA (US);
Guillermo Moreno-Sanz, Irvine, CA (US);
Tiziano Bandiera, Gambolo, IT;
Marco Mor, Ghedi, IT;
Giorgio Tarzia, Petriano, IT;
The Regents of the University of California, Oakland, CA (US);
Fondazione Istituto Italiano di Technologia, Genoa, IT;
Universita Degli Studi di Urbino “Carlo Bo”, Urbino, IT;
Universita Degli Studi di Parma, Parma, IT;
Abstract
The present invention provides methods of making and using peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH). The present invention provides compounds and compositions that suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS). The present invention also sets forth methods for inhibiting FAAH as well as methods for treating conditions such as, but not limited to, pain, inflammation, immune disorders, dermatitis, mucositis, the over reactivity of peripheral sensory neurons, neurodermatitis, and an overactive bladder. Accordingly, the invention also provides compounds, methods, and pharmaceutical compositions for treating conditions in which the selective inhibition of peripheral FAAH (as opposed to CNS FAAH) would be of benefit.