The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2017
Filed:
Apr. 07, 2011
Applicants:
Ethan Settembre, Lexington, MA (US);
Angelica Medina-selby, San Francisco, CA (US);
Doris Coit, Petaluma, CA (US);
Philip R. Dormitzer, Weston, MA (US);
Inventors:
Ethan Settembre, Lexington, MA (US);
Angelica Medina-Selby, San Francisco, CA (US);
Doris Coit, Petaluma, CA (US);
Philip R. Dormitzer, Weston, MA (US);
Assignee:
Norvartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/23 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/23 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/53 (2013.01); C12N 2750/14222 (2013.01); C12N 2750/14223 (2013.01); C12N 2750/14243 (2013.01); C12N 2830/20 (2013.01); C12N 2830/34 (2013.01);
Abstract
The invention provides a process for generating parvovirus VP1/VP2 virus like particles (VLPs). The invention further provides methods for purification of the parvovirus VLPs and immunogenic compositions that contain the VLPs. The invention also includes recombinant nucleic acid molecules that encode parvovirus VP1 and VP2, and host cells that contain the recombinant nucleic acids.