The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2017

Filed:

Aug. 31, 2007
Applicants:

Avinash Nangia, Sharon, MA (US);

Daya D. Verma, Edison, NJ (US);

Jules Jacob, Taunton, MA (US);

Inventors:

Avinash Nangia, Sharon, MA (US);

Daya D. Verma, Edison, NJ (US);

Jules Jacob, Taunton, MA (US);

Assignee:

Supernus Pharmaceuticals, Inc., Rockville, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/22 (2006.01); A61K 9/28 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 9/50 (2006.01); A61K 31/357 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2846 (2013.01); A61K 9/1635 (2013.01); A61K 9/2013 (2013.01); A61K 9/2054 (2013.01); A61K 9/2077 (2013.01); A61K 9/2086 (2013.01); A61K 9/4808 (2013.01); A61K 9/4891 (2013.01); A61K 9/5073 (2013.01); A61K 31/357 (2013.01);
Abstract

The present invention is directed to pharmaceutical compositions that allow for once-daily or alternate day dosage forms of topiramate. The proposed delayed/extended release single dosage form is equivalent to the immediate-release multiple dose daily regimen, and upon administration, provides steady state blood levels of topiramate. Formulations with increased bioavailability and improved pharmacokinetics are disclosed. A once-a-day administration of topiramate is advantageous over the multiple dose regimen both in terms of patient compliance and reduced adverse events, thus providing better treatment of the conditions for which the topiramate is indicated.


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