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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9743646 B1

PDFFull Text
Date of Patent:
Aug. 29, 2017

Filed:

Apr. 06, 2015

Method of establishing isogenic multi-xenograft model and the use thereof

Applicant:

Crown Bioscience Inc. (Taicang), Taicang, CN;

Inventors:

Qian Shi, Taicang, CN;

Yanmei Sun, Taicang, CN;

Assignee:

CROWN BIOSCIENCE INC. (TAICANG), Taicang, CN;

Attorneys:

Jun He Law Offices P.C.

James J. Zhu

Primary Examiner:

Doug Schultz

Int. Cl.
CPC ...
A01K 67/027 (2006.01); A61K 48/00 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0271 (2013.01); A61K 49/0008 (2013.01); A01K 2207/12 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01);
Abstract

The present invention provides an immuno-deficient animal useful as an animal model for a human disease associated with a first mutation of a target gene, wherein the animal comprises (a) a first human xenograft comprising the target gene comprising the first mutation; (b) a second human xenograft comprising the target gene but lacking the first mutation, wherein the first human xenograft and second human xenograft are isogenic. Also provided here are methods of producing the animal model and methods of using such animal model.

Find Patent Forward Citations

Shi, Qian. (2017). Method of establishing isogenic multi-xenograft model and the use thereof (U.S. Patent No. 9743646). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9743646

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