The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2017
Filed:
May. 07, 2004
Applicants:
Philippa Radcliffe, Oxford, GB;
James E. Miskin, Oxford, GB;
Fraser J. Wilkes, Oxford, GB;
Kyriacos A. Mitrophanous, Oxford, GB;
Susan M. Kingsman, Oxford, GB;
Inventors:
Philippa Radcliffe, Oxford, GB;
James E. Miskin, Oxford, GB;
Fraser J. Wilkes, Oxford, GB;
Kyriacos A. Mitrophanous, Oxford, GB;
Susan M. Kingsman, Oxford, GB;
Assignee:
Oxford BioMedica (UK) Limited, Oxford, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/867 (2006.01); C12N 15/11 (2006.01); C12N 7/00 (2006.01); A61K 48/00 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 48/00 (2013.01); C12N 2740/15043 (2013.01); C12N 2830/003 (2013.01); C12N 2830/008 (2013.01); C12N 2830/50 (2013.01); C12N 2830/85 (2013.01); C12N 2840/20 (2013.01); C12N 2840/203 (2013.01); C12N 2840/44 (2013.01);
Abstract
Provided is a multicistronic retroviral vector genome having a first nucleic acid sequence upstream of at least one internal regulatory element, such that the level of genomic RNA available for packaging in the absence of rev, or a functional equivalent thereof, is increased.