The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2017
Filed:
Oct. 19, 2015
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Jerusalem, IL;
Inventors:
Aviad Levin, Holon, IL;
Zvi Hayouka, Jerusalem, IL;
Assaf Friedler, Mevaseret Zion, IL;
Abraham Loyter, Jerusalem, IL;
Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12N 9/12 (2006.01); A61K 38/16 (2006.01); C07K 14/005 (2006.01); A61K 38/45 (2006.01); A61K 45/06 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1276 (2013.01); A61K 38/162 (2013.01); A61K 38/45 (2013.01); A61K 45/06 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); C07K 2319/10 (2013.01); C12N 2740/16222 (2013.01); C12Y 207/07049 (2013.01);
Abstract
Isolated peptides comprising sequences derived from the protein integrase of HIV-1, as well as their analogs, mixtures, conjugates with permeability enhancing moieties, and pharmaceutical compositions are disclosed. The peptides and compositions are capable of selectively killing HIV-1 infected cells and are used in treatment of HIV infection and AIDS.