The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2017

Filed:

Nov. 13, 2014
Applicants:

F. Hoffmann-la Roche Ag, Basel, CH;

Institut Pasteur, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Commissariat a L'energie Atomique ET Aux Energies Alternatives, Paris, FR;

Inventors:

Pierre Lafaye, Malakoff, FR;

Sylvie Bay, Paris, FR;

Benoit Delatour, Cachan, FR;

Marc Dhenain, Limours, FR;

Charles Duyckaerts, Saint-mande, FR;

Tengfei Li, Courbevoie, FR;

Matthias Vandesquille, Fontenay-aux-roses, FR;

Christian Czech, Grenzach-wyhlen, DE;

Fiona Grueninger, Arlesheim, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); G01N 33/68 (2006.01); A61K 49/16 (2006.01); C07H 21/04 (2006.01); A61K 47/48 (2006.01); A61K 51/10 (2006.01); A61K 49/00 (2006.01); A61K 49/10 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 47/48538 (2013.01); A61K 49/0058 (2013.01); A61K 49/108 (2013.01); A61K 49/16 (2013.01); A61K 51/1018 (2013.01); G01N 33/6896 (2013.01); A61K 2039/505 (2013.01); C07K 2317/22 (2013.01); C07K 2317/51 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/92 (2013.01); G01N 2333/4709 (2013.01); G01N 2800/2821 (2013.01); G01N 2800/387 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention relates to variable domain of a camelid heavy-chain antibodies directed to amyloid β and conjugates thereof. The present invention also relates to the use of these antibody conjugates for treating or diagnosing disorders mediated by amyloid β deposits.


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