The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2017

Filed:

Jun. 17, 2013
Applicant:

Daiichi Sankyo Company, Limited, Tokyo, JP;

Inventors:

Makoto Koizumi, Tokyo, JP;

Koji Morita, Tokyo, JP;

Miho Sato, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/00 (2006.01); C07H 19/22 (2006.01); C07H 23/00 (2006.01); C07F 7/10 (2006.01); C07H 19/16 (2006.01);
U.S. Cl.
CPC ...
C07H 23/00 (2013.01); C07F 7/10 (2013.01); C07H 19/16 (2013.01); Y02P 20/55 (2015.11);
Abstract

A compound represented by the general formula (III) which serves as an intermediate of an oligonucleotide analog having stable and excellent antisense or antigene activity or having excellent activity as a detection reagent (probe) for a specific gene or as a primer for the initiation of amplification of a specific gene can be produced at high yields regardless of the type of nucleobase by a method comprising reacting a compound represented by the general formula (II) or a salt thereof with a trimethylsilylated compound obtained from a compound represented by the general formula (IVb), wherein X, Y, Z, A, R, and B are as defined in claim


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