The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2017

Filed:

Oct. 29, 2015
Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Ronald T. Raines, Madison, WI (US);

Ian Windsor, Wisconsin Rapids, WI (US);

Michael Palte, Melrose, MA (US);

John Lukesh, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/34 (2006.01); A61K 31/69 (2006.01); C07F 5/02 (2006.01); A61K 31/427 (2006.01); A61K 31/00 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); A61K 31/00 (2013.01); A61K 31/34 (2013.01); A61K 31/427 (2013.01); A61K 31/69 (2013.01);
Abstract

Protease inhibitors, particularly aspartyl protease inhibitors, and more particularly HIV protease inhibitors which are boronated to enhance activity or to enhance entry into cells. Compounds, prodrugs and salts thereof of this invention contain phenylboronate groups, in particular p -B(OH)-phenyl groups, benzoxaborole groups or borono-pyridyl groups or analogous groups in which the boronate group is protected. Methods for treating AIDS and ARC as well as providing a method for treating or preventing HIV infection.


Find Patent Forward Citations

Loading…