The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2017
Filed:
Apr. 03, 2015
Applicants:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Msd Italia S.r.l., Rome, IT;
Inventors:
Nigel J. Liverton, Harleysville, PA (US);
Vincenzo Summa, Pomezia, IT;
Steven Harper, Ariccia, IT;
John A. McCauley, Maple Glen, PA (US);
Joseph J. Romano, Frederick, PA (US);
Michael T. Rudd, Collegeville, PA (US);
Assignees:
MERCK SHARP & DOHME CORP., Rahway, NJ (US);
MSD ITALIA S.R.L., Rome, IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 498/22 (2006.01); C07D 498/08 (2006.01); C07D 498/18 (2006.01); C07K 5/083 (2006.01); C07K 5/087 (2006.01); A61K 31/407 (2006.01); A61K 31/4192 (2006.01); A61K 31/437 (2006.01); A61K 31/439 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07D 498/22 (2013.01); A61K 31/407 (2013.01); A61K 31/4192 (2013.01); A61K 31/437 (2013.01); A61K 31/439 (2013.01); A61K 45/06 (2013.01); C07D 498/08 (2013.01); C07D 498/18 (2013.01); C07K 5/0804 (2013.01); C07K 5/0806 (2013.01); C07K 5/0808 (2013.01); C07K 5/0812 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.