The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2017
Filed:
Mar. 15, 2013
Applicant:
Vanderbilt University, Nashville, TN (US);
Inventors:
Corey R. Hopkins, Nolensville, TN (US);
Charles C. Hong, Nolensville, TN (US);
Craig W. Lindsley, Brentwood, TN (US);
Darren W. Engers, Nashville, TN (US);
Assignee:
Vanderbilt University, Nashville, TN (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/4709 (2006.01); A61K 31/5025 (2006.01); A61K 31/519 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4709 (2013.01); A61K 31/5025 (2013.01); A61K 31/519 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract
The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation.