The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2017

Filed:

Sep. 06, 2011
Applicants:

Pei Zhou, Cary, NC (US);

Eric J. Toone, Durham, NC (US);

Inventors:

Pei Zhou, Cary, NC (US);

Eric J. Toone, Durham, NC (US);

Assignee:

Duke University, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 237/34 (2006.01); C07C 259/06 (2006.01); C07D 207/273 (2006.01); C07C 275/14 (2006.01); C07C 275/24 (2006.01); C07C 275/28 (2006.01); C07C 311/19 (2006.01); C07C 311/39 (2006.01); C07D 205/085 (2006.01); C07D 231/12 (2006.01); C07D 249/04 (2006.01); C07D 257/04 (2006.01); C07D 261/08 (2006.01); C07D 263/16 (2006.01); C07D 265/30 (2006.01); C07D 275/03 (2006.01); C07D 277/22 (2006.01); C07D 295/155 (2006.01); C07D 307/36 (2006.01); C07D 333/06 (2006.01); C07C 311/37 (2006.01); C07D 209/20 (2006.01); C07D 213/73 (2006.01); C07D 233/64 (2006.01);
U.S. Cl.
CPC ...
C07D 207/273 (2013.01); C07C 237/34 (2013.01); C07C 259/06 (2013.01); C07C 275/14 (2013.01); C07C 275/24 (2013.01); C07C 275/28 (2013.01); C07C 311/19 (2013.01); C07C 311/37 (2013.01); C07C 311/39 (2013.01); C07D 205/085 (2013.01); C07D 209/20 (2013.01); C07D 213/73 (2013.01); C07D 231/12 (2013.01); C07D 233/64 (2013.01); C07D 249/04 (2013.01); C07D 257/04 (2013.01); C07D 261/08 (2013.01); C07D 263/16 (2013.01); C07D 265/30 (2013.01); C07D 275/03 (2013.01); C07D 277/22 (2013.01); C07D 295/155 (2013.01); C07D 307/36 (2013.01); C07D 333/06 (2013.01);
Abstract

Disclosed are compounds of formulae (I), (II), and (II)I: and pharmaceutically acceptable salts thereof, wherein the variables, R, R, R, R, R, L, D, Q, Y, X, and Z are defined herein. These compounds are useful for treating Gram-negative bacteria infections.


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