The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2017
Filed:
Nov. 15, 2016
Applicant:
Hong Kong Baptist University, Kowloon, HK;
Inventors:
Assignee:
Hong Kong Baptist University, Hong Kong, HK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/09 (2006.01); C07C 43/23 (2006.01); C07C 39/16 (2006.01); C07C 37/00 (2006.01); C07C 39/15 (2006.01);
U.S. Cl.
CPC ...
C07C 43/23 (2013.01); A61K 31/09 (2013.01); C07C 37/003 (2013.01); C07C 39/15 (2013.01); C07C 39/16 (2013.01);
Abstract
A polyphenol derivative of the stilbenoid family, namely trans-3,5,4'-trihydroxybibenzyl, also known as dihydro-resveratrol, is disclosed as a remedial agent. In particular, the usage of dihydro-resveratrol as an anti-fibrotic agent in suppressing the activation of pancreatic stellate cells (PSCs) is presented. One embodiment also relates to the management of pancreatic fibrosis, which is often accompanied with chronic pancreatitis and desmoplastic reaction of pancreatic cancer. Another embodiment has applications in preventing or alleviating or treating pancreatic cancer or pancreatogenic diabetes.