The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2017

Filed:

Nov. 20, 2015
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Luke P. Lee, Orinda, CA (US);

Debkishore Mitra, Berkeley, CA (US);

John R. Waldeisen, Berkeley, CA (US);

Jixiao Liu, Albany, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/00 (2006.01); B01L 3/00 (2006.01); B01D 19/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502723 (2013.01); B01D 19/0031 (2013.01); B01L 3/50273 (2013.01); B01L 2200/0684 (2013.01); B01L 2300/069 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/0883 (2013.01); B01L 2300/10 (2013.01); B01L 2300/12 (2013.01); B01L 2300/123 (2013.01); B01L 2400/049 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0605 (2013.01); B01L 2400/0638 (2013.01); B01L 2400/0694 (2013.01);
Abstract

An apparatus with a self-contained, tunable, microfluidic pumping system that utilizes the high air permeability of the matrix material to actuate fluid flow in a network of fluidic microchannels and microstructures is provided. The pumping relies upon partial evacuation of degas/vacuum channels that are located next to the fluid channels to degas air from the fluid channels or structures producing a reduction of pressure in the fluidic channel leading to the flow of fluid from an inlet at atmospheric pressure through the device. The solution is isolated from the pumping apparatus since the liquid does not pass through the diffusion barriers. The apparatus and method can also provide bubble-free microfluidic pumping, without any auxiliary equipment or device pre-treatment, and can fill dead-end channels and chambers, providing a powerful liquid handling tool for a broad range of applications.


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