The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2017

Filed:

Apr. 22, 2014
Applicant:

Advanced Accelerator Applications S.a.;

Inventors:

Luca Domenico D'Andrea, Naples, IT;

Carlo Pedone, Naples, IT;

Maria Caterina Turco, Avellino, IT;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61K 49/00 (2006.01); A61K 38/08 (2006.01); A61K 38/00 (2006.01); A61K 38/04 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); A61K 49/14 (2006.01); C07K 14/52 (2006.01); A61K 38/10 (2006.01);
U.S. Cl.
CPC ...
A61K 49/14 (2013.01); A61K 38/10 (2013.01); A61K 49/0002 (2013.01); C07K 14/52 (2013.01); A61K 38/00 (2013.01);
Abstract

Compounds of general formula (1): X1Y1X2Y2X3Y3X4Y4Y5X5X6Y6X7Y7X8X9X10 wherein X1-X10 are any natural or unnatural amino acids and Y1 is Gln; Y2 is Met or Leu; Y3 is He; Y4 is Pro or Ser; Y5 is His or Gly; Y6 is Gln or Pro; Y7 is He or Tyr or their homolog or ortolog are described; these compounds are able to bind to the VEGF receptors and to modulate the angiogenesis mediated by the VEG.


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