The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2017

Filed:

Nov. 26, 2013
Applicant:

Kythera Biopharmaceuticals, Inc., Calabasas, CA (US);

Inventors:

Robert Emil Hodge, McPherson, KS (US);

Jeffrey Douglas Webster, Thousand Oaks, CA (US);

Robert M. Moriarty, Michiana Shores, IN (US);

Assignee:

Kythera Biopharmaceuticals, Inc., Parsippany, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/57 (2006.01); A61K 31/575 (2006.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01);
U.S. Cl.
CPC ...
A61K 31/575 (2013.01); A61K 9/0019 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01);
Abstract

The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.


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