The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2017
Filed:
Dec. 17, 2014
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Merck Canada Inc., Kirkland, CA;
John A. McCauley, Maple Glen, PA (US);
Christian Beaulieu, Laval, CA;
David Jonathan Bennett, Boston, MA (US);
Christopher J. Bungard, Lansdale, PA (US);
Sheldon Crane, Ile Perrot, CA;
Thomas J. Greshock, Collegeville, PA (US);
Katharine M. Holloway, Lansdale, PA (US);
Helen Juteau, Ville St-Laurent, CA;
Daniel McKay, Milton, MA (US);
Carmela Molinaro, Rahway, NJ (US);
Oscar Miguel Moradei, Kirkland, CA;
Christian Nadeau, Montreal, CA;
Daniel Simard, Montreal, CA;
Satyanarayana Tummanapalli, Singapore Science Park III, SG;
Vouy Linh Truong, Pierrefonds, CA;
Karine M. Villeneuve, Montreal, CA;
Peter D. Williams, Harleysville, PA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Merck Canada Inc., Kirkland, Quebec, CA;
Abstract
The present invention is directed to 5-heteroarylmorpholine derivatives and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.