The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2017

Filed:

Aug. 07, 2013
Applicant:

Emory University, Atlanta, GA (US);

Inventors:

Stephen F. Traynelis, Decatur, GA (US);

Praseeda Mullasseril, Rockville, MD (US);

Ethel C Garnier, Tucker, GA (US);

Dennis C. Liotta, Atlanta, GA (US);

Sommer Zimmerman, Clarkston, GA (US);

Assignee:

Emory University, Atlanta, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/444 (2006.01); A61K 31/404 (2006.01); A61K 31/4015 (2006.01); A61K 31/4439 (2006.01); A61K 45/06 (2006.01); C07D 207/38 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/444 (2013.01); A61K 31/404 (2013.01); A61K 31/4015 (2013.01); A61K 31/4439 (2013.01); A61K 45/06 (2013.01); C07D 207/38 (2013.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 409/14 (2013.01);
Abstract

This disclosure relates to NMDA modulators and used related thereto such as for treatment of central nervous system disorders. In certain embodiments, compounds disclosed herein are NR2C subunit-selective NMDA potentiators. In certain embodiments, the disclosure contemplates compounds and pharmaceutical compositions. In certain embodiments, the disclosure contemplates compounds disclosed herein as prodrugs, optionally substituted with one or more substituents, derivatives, or salts thereof. In certain embodiments, the disclosure relates to methods of treating or preventing nervous system disorders comprising administering an effective amount of a composition comprising compound disclosed herein to a subject in need thereof.


Find Patent Forward Citations

Loading…