The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
May. 27, 2011
Applicants:
Yu-chong Tai, Pasadena, CA (US);
BO LU, Pasadena, CA (US);
Inventors:
Yu-Chong Tai, Pasadena, CA (US);
Bo Lu, Pasadena, CA (US);
Assignee:
CALIFORNIA INSTUTE OF TECHNOLOGY, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); G01N 33/50 (2006.01); B01D 63/08 (2006.01); B01D 65/10 (2006.01); B01D 67/00 (2006.01); C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); B01D 63/087 (2013.01); B01D 65/10 (2013.01); B01D 67/0034 (2013.01); B01D 2325/021 (2013.01); C12M 47/04 (2013.01);
Abstract
The present invention provides methods for designing a filtration systems for capturing viable tumor cells, such as circulating tumor cells at high efficiency and high viability. The methods involve development of a set of 'key engineering design parameters' that are crucial to achieve high tumor cell viability. These important design parameters include the filter geometry design, fluid delivery method, transfilter pressure and total filtration time.