The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2017

Filed:

Jul. 25, 2013
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

John Leite, Vista, CA (US);

Robert Pope, Coralville, IA (US);

Mahbod Hajivandi, Vista, CA (US);

Xiquan Liang, Escondido, CA (US);

Assignee:

LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G01N 27/62 (2006.01); G01N 33/60 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 27/62 (2013.01); G01N 33/60 (2013.01); G01N 33/6848 (2013.01); G01N 33/6851 (2013.01); G01N 2458/15 (2013.01); Y10T 436/24 (2015.01);
Abstract

The invention provides methods for quantifying biomolecules, such as polypeptides in mass spectrometric analysis. The methods include use of a biomolecule standard having at least one atomic isotope different than that of the naturally occurring isotopes in the biomolecule of interest. Methods of the present invention also include methods for quantifying biomolecules where the copy biomolecule standard is made by expressing the biomolecule using a recombinant cell. Further included are the biomolecule standards themselves, method for making such standards, kits, systems, reagents, and engineered cells relating to the use of biomolecule standards in mass spectrometric analysis.


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