The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
Sep. 02, 2011
Jianfeng Xu, Clemmons, NC (US);
Siqun Lilly Zheng, Clemmons, NC (US);
Jielin Sun, Oak Ridge, NC (US);
Andrew Karim Kader, San Diego, CA (US);
Jianfeng Xu, Clemmons, NC (US);
Siqun Lilly Zheng, Clemmons, NC (US);
Jielin Sun, Oak Ridge, NC (US);
Andrew Karim Kader, San Diego, CA (US);
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Abstract
The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample obtained from the subject and determining a genotype for the subject at a plurality of biallelic polymorphic loci, wherein each of said plurality has an associated allele and an unassociated allele, wherein the genotype is selected from the group consisting of homozygous for the associated allele, heterozygous, and homozygous for the unassociated allele; and b) calculating a cumulative relative risk (CRR) for the subject based on the genotype determined in step (a). A CRR of greater than 1.00 identifies a subject as having an increased risk of developing prostate cancer and also can identify a subject who is a candidate for early PSA screening, prostate biopsy and/or chemoprevention.