The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9732388 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 15, 2017

Filed:

Dec. 26, 2014
Applicant:

Guangzhou Sagene Biotech Corp., Guangzhou, Guangdong, CN;

Inventors:

Hongling Jia, Guangdong, CN;

Gong Zhang, Guangdong, CN;

Chaowu Liu, Guangdong, CN;

Li Zhang, Guangdong, CN;

Jie Chen, Guangdong, CN;

Hongbin Zeng, Guangdong, CN;

Minfei Yu, Guangdong, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract

The present invention provides nucleic acid markers for rapid diagnosis of KD and a kit for detection of the nucleic acid markers. The nucleic acid markers are 4 miRNAs, and the kit comprises primers for quantitative detection of the 4 miRNAs by fluorescent quantitative PCR. The diagnosis of KD can be performed only by quantificationally detecting the contents of the 4 miRNAs in serum exosomes and then analyzing the Ct values of the 4 miRNAs. The present invention possesses the advantages of easily-obtained sample, simple operation, high specificity, time saving, accurate and reliable detection result, etc., so children with KD can be timely and accurately diagnosed. Particularly, KD can be easily distinguished from common virus infection with similar symptoms only by one test. The present invention may play an important role in rapid diagnosis of KD of children and further provide a direction for developing rapid diagnostic kit of KD.


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Jia, Hongling. (2017). Nucleic acid markers for rapid diagnosis of kawasaki disease and kit for detection of the nucleic acid markers (U.S. Patent No. 9732388). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9732388

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