The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2017

Filed:

Sep. 04, 2014
Applicant:

Tocagen Inc., San Diego, CA (US);

Inventors:

Harry E. Gruber, Rancho Santa Fe, CA (US);

Douglas J. Jolly, Encinitas, CA (US);

Omar D. Perez, San Diego, CA (US);

Christopher R. Logg, South Pasadena, CA (US);

Assignee:

Tocagen Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 31/513 (2006.01); A61K 38/22 (2006.01); C12N 9/78 (2006.01); C12N 15/86 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 31/513 (2013.01); A61K 38/2292 (2013.01); A61K 48/00 (2013.01); C12N 9/78 (2013.01); C12N 15/86 (2013.01); C12N 2740/13043 (2013.01); C12N 2760/16021 (2013.01); C12N 2760/16032 (2013.01); C12N 2760/16043 (2013.01);
Abstract

This disclosure provides modified cytosine deaminases (CDs). The disclosure further relates to cells and vector expressing or comprising such modified CDs and methods of using such modified CDs in the treatment of disease and disorders.


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