The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2017

Filed:

Oct. 23, 2009
Applicants:

Anne Moscona, New York, NY (US);

Matteo Porotto, New York, NY (US);

David Alexander Lavan, Rockville, MD (US);

Feng Yi, Rockville, MD (US);

Inventors:

Anne Moscona, New York, NY (US);

Matteo Porotto, New York, NY (US);

David Alexander LaVan, Rockville, MD (US);

Feng Yi, Rockville, MD (US);

Assignee:

Cornell University, Ithaca, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); A61K 39/155 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); C12N 2760/18261 (2013.01);
Abstract

The invention provides a method of reducing viral infectivity in a sample comprising contacting the sample with a earner matrix wherein lipids are attached to the carrier matrix, and wherein at least one virus-specific agent is attached to the lipids The virus-specific agent is capable of binding to at least one viral component The virus specific agent may be a receptor The earner matrix may be a silica particle, which may be coated with a lipid bilayer The invention further provides a method of inactivating a virus comprising contacting the virus with a earner matrix wherein lipids are attached to the earner matrix, and wherein at least one receptor is attached to the lipids, binding the receptor to at least one viral receptor-binding protein, and activating at least one viral fusion protein, wherein activation inactivates the virus, and releases the virus from the earner matrix.


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