The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2017

Filed:

Dec. 10, 2015
Applicant:

University of Georgia Research Foundation, Inc., Athens, GA (US);

Inventors:

Stephen Dalton, Athens, GA (US);

David Reynolds, Kilsyth, AU;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); A61K 35/12 (2015.01); A61P 9/00 (2006.01); C12N 5/071 (2010.01); C12N 5/0735 (2010.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12N 5/0606 (2013.01); C12N 5/069 (2013.01); C12N 5/0656 (2013.01); C12N 5/0661 (2013.01); C12N 5/0662 (2013.01); C12N 5/0692 (2013.01); C12N 2501/105 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/155 (2013.01); C12N 2501/16 (2013.01); C12N 2501/165 (2013.01); C12N 2501/195 (2013.01); C12N 2501/415 (2013.01); C12N 2501/727 (2013.01); C12N 2502/13 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01); C12N 2533/78 (2013.01); C12N 2533/90 (2013.01);
Abstract

The present invention relates to inter alia, methods for the generation and maintenance of Mesoderm-derived ISL1+ Multipotent Progenitors (IMPs), the production of a number of pluripotent cells including and epicardial pluripotent cells (EPCs) and using these cells to produce endothelial cells, cardiomyocytes, smooth muscle cells, vascular cells and other cells and related methods as otherwise disclosed herein. The invention also relates to compositions comprising a population of cells.


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