The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
Jul. 12, 2013
Applicant:
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Inventors:
Assignee:
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); G01N 33/574 (2006.01); C12N 9/02 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); C07K 14/4702 (2013.01); C12N 9/0051 (2013.01); C12Y 108/01008 (2013.01); G01N 33/5308 (2013.01); G01N 33/57484 (2013.01); C07B 2200/13 (2013.01); G01N 2500/02 (2013.01); G01N 2500/04 (2013.01);
Abstract
The present invention relates to a modified TXNIP protein, a method for preparing the modified TXNIP protein, a polynucleotide encoding the modified protein, an expression vector including the polynucleotide, a transformant introduced with the expression vector, a method for crystallizing a modified TRX-TXNIP complex using the modified TXNIP protein, and a method for screening a substance regulating interaction between TRX and TXNIP, an inhibitor of TRX activity, or a substance regulating TXNIP function.